Putative environmental-endocrine disruptors and obesity: a review
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چکیده
منابع مشابه
Putative environmental-endocrine disruptors and obesity: a review.
PURPOSE OF REVIEW There has been a substantial increase in the prevalence of obesity in the last several decades. Recent evidence suggests that endocrine-disrupting chemicals, for example halogenated aromatic hydrocarbons, may cause perturbations in endogenous hormonal regulation and alter other mechanisms involved in weight homeostasis, which may lead to weight gain by increased volume of adip...
متن کاملEndocrine Disruptors and Obesity
PURPOSE OF REVIEW The purpose of this review was to summarise current evidence that some environmental chemicals may be able to interfere in the endocrine regulation of energy metabolism and adipose tissue structure. RECENT FINDINGS Recent findings demonstrate that such endocrine-disrupting chemicals, termed "obesogens", can promote adipogenesis and cause weight gain. This includes compounds ...
متن کامل[Endocrine disruptors and obesity: obesogens].
Incidence and prevalence of owerweight and obesity have greatly increased over the past three decades in almost all countries around the world. This phenomenon is not easily explained by lifestyle changes in populations with very different initial habits. This has led to consider the influence of other factors, the so-called endocrine disruptors, and more specifically obesogens. This study revi...
متن کاملMany Putative Endocrine Disruptors Inhibit Prostaglandin Synthesis
BACKGROUND Prostaglandins (PGs) play key roles in development and maintenance of homeostasis of the adult body. Despite these important roles, it remains unclear whether the PG pathway is a target for endocrine disruption. However, several known endocrine-disrupting compounds (EDCs) share a high degree of structural similarity with mild analgesics. OBJECTIVES AND METHODS Using cell-based tran...
متن کاملEnvironmental Thyroid Disruptors and Human Endocrine Health
In the last 30 years, there is increasing concern about chemical pollutants that have the ability to act as hormone mimics. Because of structural similarity with endogenous hormones, their ability to interact with hormone transport proteins, or their ability to disrupt hormone metabolism, these environmental chemicals have the potential mimic, or in some cases block, the effects of endogenous h...
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ژورنال
عنوان ژورنال: Current Opinion in Endocrinology, Diabetes and Obesity
سال: 2008
ISSN: 1752-296X
DOI: 10.1097/med.0b013e32830ce95c